It will be interesting to see which Aprilia bits find their way into Can-Am Spyder engines. The good news is the after market has lots of possibilities from the get-go! Note in this older article listing tweaked items (including dry sump) in the Mille:
"... You may be familiar with the Mille, but let's go through the specification sheet, nonetheless. The sixty degree v-twin has four valves per cylinder and double-overhead cams. It is fed by 51mm throttle bodies through an electronic fuel injection system featuring one injector per cylinder. The engine also features twin spark plugs per cylinder (for more efficient combustion) and dry sump lubrication for a more rigid and compact engine sump (a feature found on many race bikes).
Aprilia also justifiably brags about its patented vibration reduction system (sixty degree v-twins can be pretty unruly -- but this machine is silky smooth) and its carefully developed clutch (featuring "pneumatic power") to control rear wheel bounce.
The only difference between the engine in the Tuono and the engine in the Mille superbike is a slightly different intake manifold design and engine mapping. Having ridden the Mille R, the Tuono feels just as quick and, perhaps, even smoother than its superbike sibling..."